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Selye, progesterone

thymus

3 comments… add one
  • Bukowski 22/10/2014, 6:10 am
  • Jasper 31/12/2014, 7:41 am

    All three studies show the effects of progestines (and estrogens), not progesterone. There are however studies regarding immune response and progesterone. The effects are the opposite. Progesterone is protective.

    As for the quotation above: I have read Hans Selye and never come across any mentioning of progesterone and the ATROPHY of the thymus. Selye did use the size of the thymus gland for prognostics. He noticed a thymus atrophy caused by too much insulin and other stress responses. He also discovered the protective effects of the “luteoids” as he called progesterone.

    I know of a woman who used natural progesterone when she was treated for breast cancer. Her thymus gland was very much enlarged after about a month. I am rather sure this was not the effect of her chemotherapy.

    “(Selye’s) biggest disappointment, nevertheless, was
    probably the lack of appreciation for his first modern
    classification and naming of steroid hormones as well
    as the discovery of anti-inflammatory actions of
    glucocorticoids (Selye 1941a, b, 1942, 1943b). He
    cleverly named these hormones by their sources, e.g.
    corticoids (originating in the adrenal cortex), testoids
    (from the testes), and folliculoids and luteoids
    (produced by the follicles and corpus luteum of the
    ovary, respectively).”

    The legacy of Hans Selye and the origins of stress research:
    A retrospective 75 years after his landmark brief “Letter” to the Editor of Nature, 2012

    http://digitool.library.colostate.edu///exlibris/dtl/d3_1/apache_media/L2V4bGlicmlzL2R0bC9kM18xL2FwYWNoZV9tZWRpYS8xMjk3NTY=.pdf

    http://www.sagepub.com/upm-data/44175_2.pdf

  • Edward 03/01/2015, 11:48 am

    Thymus hypertrophy is not a good thing. As well, thymus hypertrophy does occur with chemotherapy treatment. When looking at the functional mechanisms of progesterone it is useful to understand how abortions work and what is going on with the immune system during pregnancy.

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