Adaptive systems · Essential fatty acid biochemistry · Hormetic endocrinology
Context is everything—in tissue, in data, in life. Twenty years as a scientist in histotechnology taught me to look closer, question assumptions, and find the signal in the noise. Decompile obsession.
Essays
All essays →- Merchants of Doubt
The manufactured architecture of American anti-intellectualism. How identifiable actors spent decades and billions manufacturing doubt about expertise—and built a trillion-dollar parallel economy on the result.
- Hormetic Endocrinology
Chronic testosterone replacement creates dependency through HPG axis suppression. Brief cyclical perturbation may preserve or enhance baseline function—a hormetic approach to endocrinology with falsifiable predictions.
- Consolidation Amplifiers
If racetams enhance cholinergic function, they should specifically improve how well adaptations consolidate after training. A framework for thinking about timing.
- Essential Architecture
You don't burn lumber while your walls are falling down. PUFAs aren't fuel—they're building blocks that cause problems in the wrong metabolic context.
- Systems at the Edge
Complex systems survive in a narrow band between rigidity and chaos. From Prigogine to Taleb—the same patterns keep emerging.
- The Integrated System
Velocity, stability, form, and consolidation aren't separate ideas—they're components of one system. Here's how the pieces fit together.
- Thyroid Hormone as the Guardian of Form
The cell maintains its shape against entropy through continuous energy flux. T3 is the conductor of this anti-entropic effort—not a metabolic accelerator, but a structural organizer.
- When Architecture Fails
From double bonds to metabolic crisis—why essential fatty acids are essential, how they're consumed, and what breaks when replacement can't keep pace.