Essays
Browse Edward J. Edmonds’s essays on hormone signaling, adaptation, membrane architecture, and the systems that shape biological and public life.
2026
- Essential Fatty Acids: There Is a Lot to Explain
How stress, food supply, and metabolism shape essential fatty acid adequacy: an introduction to a century of research on linoleic acid, deficiency, and adaptation.
- Merchants of Doubt
An analysis of how corporate incentives, political strategy, and media amplification manufacture doubt and erode public trust in expertise.
- When Architecture Fails
An essay tracing proposed links between essential fatty acids, cardiolipin damage, mitochondrial dysfunction, and disrupted thyroid signaling.
- Essential Fatty Acids: There Is a Lot to Explain
2025
- Essential Architecture
An argument for distinguishing the structural roles of essential fatty acids from fuel use, connecting membrane maintenance with metabolic function.
- Systems at the Edge
An essay extending an adaptive physiology framework to organizations, learning, and relationships through ideas from complex systems theory.
- The Integrated System
A synthesis of velocity, stability, signal quality, and consolidation into a framework for adaptive physiology and its proposed failure modes.
- Thyroid Hormone as the Guardian of Form
A theoretical account of thyroid signaling, energy metabolism, and cellular form, exploring how fuel availability and membrane integrity constrain function.
- Consolidation Amplifiers
An essay exploring whether racetams and cholinergic signaling could influence how training adaptations consolidate within an endocrine framework.
- Hormetic Endocrinology
A theoretical framework for cyclical hormone signaling, recovery, and adaptation, with explicit hypotheses, uncertainties, and testable predictions.
- Essential Architecture